Papers
2021
Saforo Amponsah P, Yahya G, Zimmermann J, Mai M, Mergel S, Mühlhaus T, Storchova Z, Morgan B (2021) Peroxiredoxins couple metabolism and cell division in an ultradian cycle. Nature Chemical Biology 17:477-484.
Niemeyer J, Scheuring D, Oestreicher J, Morgan B, Schroda M (2021) Real-time Monitoring of Subcellular H2O2 Distribution in Chlamydomonas reinhardtii. Plant Cell Epub ahead of print. PMID: 3419671.
Zimmermann J, Oestreicher J, Geissel F, Deponte M, Morgan B (2021) An intracellular assay for activity screening and characterization of glutathione-dependent oxidoreductases. Plant Cell 172:340-349.
Niemeyer J, Scheuring D, Oestreicher J, Morgan B, Schroda M (2021) Real-time Monitoring of Subcellular H2O2 Distribution in Chlamydomonas reinhardtii. Plant Cell Epub ahead of print. PMID: 3419671.
Zimmermann J, Oestreicher J, Geissel F, Deponte M, Morgan B (2021) An intracellular assay for activity screening and characterization of glutathione-dependent oxidoreductases. Plant Cell 172:340-349.
2020
Vilas-Boas EA, Nalbach L, Ampofo E, Ferraz Lucena C, Naudet L, Ortis F, Carpinelli AR, Morgan B, Roma LP (2020) Transient NADPH oxidase 2-dependent H2O2 production drives early palmitate-induced lipotoxicity in pancreatic islets. Free Radical Biology and Medicine 162:1-13.
Silina YE, Morgan B (2020) LDI-MS scanner: Laser desorption ionization mass spectrometry-based biosensor standardization. Talanta 223:121688.
Steinbeck J, Fuchs P, Negroni YL, Elsässer M, Lichtenauer S, Stockdreher Y, Feitosa Araújo E, Kroll JB, Niemeier JO, Humberg C, Smith EN, Mai M, Nunes-Nesi A, Meyer AJ, Zottini M, Morgan B, Wagner S, Schwarzländer M. (2020) In Vivo NADH/NAD+ Biosensing Reveals the Dynamics of Cytosolic Redox Metabolism in Plants. Plant Cell tpc 32:3324-3345.
Yap YW, Rusu PM, Chan AY, Fam BC, Jungmann A, Solon-Biet SM, Barlow CK, Creek DJ, Huang C, Schittenhelm RB, Morgan B, Schmoll D, Kiens B, Piper MDW, Heikenwälder M, Simpson SJ, Bröer S, Andrikopoulos S, Müller OJ, Rose AJ (2020) Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution. Nature communications 11:2894.
Zimmermann J, Oestreicher J, Hess S, Herrmann JM, Deponte M, Morgan B (2020) One cysteine is enough: A monothiol Grx can functionally replace all cytosolic Trx and dithiol Grx. Redox biology 36:101598.
Liedgens L, Zimmermann J, Wäschenbach L, Geissel F, Laporte H, Gohlke H, Morgan B, Deponte M (2020) Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins. Nature communications 11:1725.
Vilas-Boas EA, Karabacz N, Marsiglio-Librais GN, Valle MMR, Nalbach L, Ampofo E, Morgan B, Carpinelli AR, Roma LP (2020) Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function. Pharmacological reports 72:1725–1737.
Silina YE, Morgan B (2020) LDI-MS scanner: Laser desorption ionization mass spectrometry-based biosensor standardization. Talanta 223:121688.
Steinbeck J, Fuchs P, Negroni YL, Elsässer M, Lichtenauer S, Stockdreher Y, Feitosa Araújo E, Kroll JB, Niemeier JO, Humberg C, Smith EN, Mai M, Nunes-Nesi A, Meyer AJ, Zottini M, Morgan B, Wagner S, Schwarzländer M. (2020) In Vivo NADH/NAD+ Biosensing Reveals the Dynamics of Cytosolic Redox Metabolism in Plants. Plant Cell tpc 32:3324-3345.
Yap YW, Rusu PM, Chan AY, Fam BC, Jungmann A, Solon-Biet SM, Barlow CK, Creek DJ, Huang C, Schittenhelm RB, Morgan B, Schmoll D, Kiens B, Piper MDW, Heikenwälder M, Simpson SJ, Bröer S, Andrikopoulos S, Müller OJ, Rose AJ (2020) Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution. Nature communications 11:2894.
Zimmermann J, Oestreicher J, Hess S, Herrmann JM, Deponte M, Morgan B (2020) One cysteine is enough: A monothiol Grx can functionally replace all cytosolic Trx and dithiol Grx. Redox biology 36:101598.
Liedgens L, Zimmermann J, Wäschenbach L, Geissel F, Laporte H, Gohlke H, Morgan B, Deponte M (2020) Quantitative assessment of the determinant structural differences between redox-active and inactive glutaredoxins. Nature communications 11:1725.
Vilas-Boas EA, Karabacz N, Marsiglio-Librais GN, Valle MMR, Nalbach L, Ampofo E, Morgan B, Carpinelli AR, Roma LP (2020) Chronic activation of GPR40 does not negatively impact upon BRIN-BD11 pancreatic β-cell physiology and function. Pharmacological reports 72:1725–1737.
2019
Semenova JD, Gernaey K, Morgan B, Silina YE (2019) Towards one-step design of tailored enzymatic nanobiosensors. Analyst , 145:1014-1024.
Calabrese G, Peker E, Amponsah PS, Hoehne MN, Riemer T, Mai M, Bienert GP, Deponte M, Morgan B, Riemer J (2019) Hyperoxidation of mitochondrial peroxiredoxin limits H2O2-induced cell death in yeast. EMBO J. , 38:e101552.
Oestreicher J, Morgan B (2019) Glutathione: subcellular distribution and membrane transport. Biochemistry and Cell Biology 97:270-289.
Calabrese G, Peker E, Amponsah PS, Hoehne MN, Riemer T, Mai M, Bienert GP, Deponte M, Morgan B, Riemer J (2019) Hyperoxidation of mitochondrial peroxiredoxin limits H2O2-induced cell death in yeast. EMBO J. , 38:e101552.
Oestreicher J, Morgan B (2019) Glutathione: subcellular distribution and membrane transport. Biochemistry and Cell Biology 97:270-289.
2018
Herrmann JM, Morgan B, Hansen K (2018) Disulfide Bond Formation in Mitochondria. in Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering. , Feige MJ (ed)., pp 205 - 223.
Radi R, Denicola A, Morgan B, Zielonka J (2018) Foreword to the Free Radical Biology and Medicine. Free Radical Biology and Medicine 128:1-2.
Roma LP, Deponte M, Riemer J, Morgan B (2018) Mechanisms and Applications of Redox-Sensitive Green Fluorescent Protein-Based Hydrogen Peroxide Probes. Antioxidants & Redox Signaling 29:552-568.
Staudacher V, Trujillo M, Diederichs T, Dick TP, Radi R, Morgan B, Deponte M (2018) Redox-sensitive GFP fusions for monitoring the catalytic mechanism and inactivation of peroxiredoxins in living cells. Redox Biology 14:549-556.
Radi R, Denicola A, Morgan B, Zielonka J (2018) Foreword to the Free Radical Biology and Medicine. Free Radical Biology and Medicine 128:1-2.
Roma LP, Deponte M, Riemer J, Morgan B (2018) Mechanisms and Applications of Redox-Sensitive Green Fluorescent Protein-Based Hydrogen Peroxide Probes. Antioxidants & Redox Signaling 29:552-568.
Staudacher V, Trujillo M, Diederichs T, Dick TP, Radi R, Morgan B, Deponte M (2018) Redox-sensitive GFP fusions for monitoring the catalytic mechanism and inactivation of peroxiredoxins in living cells. Redox Biology 14:549-556.
2017
Calabrese G, Morgan B, Riemer J (2017) Mitochondrial Glutathione: Regulation and Functions. Antioxidants & Redox Signaling 27:1162-1177.
Yofe I, Soliman K, Chuartzman SG, Morgan B, Weill U, Yifrach E, Dick TP, Cooper SJ, Ejsing CS, Schuldiner M, Zalckvar E, Thoms S (2017) Pex35 is a regulator of peroxisome abundance. Journal of Cell Science 130:791-804.
Morgan B, Herrmann J (2017) Disulfide bonds. in Encyclopedia of Life Sciences.
Yofe I, Soliman K, Chuartzman SG, Morgan B, Weill U, Yifrach E, Dick TP, Cooper SJ, Ejsing CS, Schuldiner M, Zalckvar E, Thoms S (2017) Pex35 is a regulator of peroxisome abundance. Journal of Cell Science 130:791-804.
Morgan B, Herrmann J (2017) Disulfide bonds. in Encyclopedia of Life Sciences.
2016
Swain L, Kesemeyer A, Meyer-Roxlau S, Vettel C, Zieseniss A, Guntsch A, Jatho A, Becker A, Nanadikar MS, Morgan B, Dennerlein S, Shah AM, El-Armouche A, Nikolaev VO, Katschinski DM (2016) Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice. Circulation Research 119:1004-1016.
Morgan B, Van Laer K, Owusu TN, Ezerina D, Pastor-Flores D, Amponsah PS, Tursch A, Dick TP (2016) Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes. Nature Chemical Biology 12:437-443.
Schwarzländer M, Dick TP, Meyer AJ, Morgan B (2016) Dissecting Redox Biology Using Fluorescent Protein Sensors. Antioxidants & Redox Signaling 24:680-712.
Morgan B, Schwarzländer M (2016) Fluoreszierende Proteinsensoren für die Redoxregulation in lebenden Zellen. BIOspektrum 22:260-263.
Morgan B, Van Laer K, Owusu TN, Ezerina D, Pastor-Flores D, Amponsah PS, Tursch A, Dick TP (2016) Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes. Nature Chemical Biology 12:437-443.
Schwarzländer M, Dick TP, Meyer AJ, Morgan B (2016) Dissecting Redox Biology Using Fluorescent Protein Sensors. Antioxidants & Redox Signaling 24:680-712.
Morgan B, Schwarzländer M (2016) Fluoreszierende Proteinsensoren für die Redoxregulation in lebenden Zellen. BIOspektrum 22:260-263.
2015
Hildebrandt T, Knuesting J, Berndt C, Morgan B, Scheibe R (2015) Cytosolic thiol switches regulating basic cellular functions: GAPDH as an information hub? Biological Chemistry 396:523-537.
Peralta D, Bronowska AK, Morgan B, Doka E, Van Laer K, Nagy P, Grater F, Dick TP (2015) A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation. Nature Chemical Biology 11:156-163.
Peralta D, Bronowska AK, Morgan B, Doka E, Van Laer K, Nagy P, Grater F, Dick TP (2015) A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation. Nature Chemical Biology 11:156-163.
2014
Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Muller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP (2014) The 'mitoflash' probe cpYFP does not respond to superoxide. Nature 514:E12-14.
Elbaz-Alon Y, Morgan B, Clancy A, Amoako TN, Zalckvar E, Dick TP, Schwappach B, Schuldiner M (2014) The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. FEMS Yeast Research 14:1055-1067.
Morgan B (2014) Reassessing cellular glutathione homoeostasis: novel insights revealed by genetically encoded redox probes. Biochemical Society Transactions 42:979-984.
Ezerina D, Morgan B, Dick TP (2014) Imaging dynamic redox processes with genetically encoded probes. Journal of molecular and cellular cardiology Journal of Molecular and Cellular Cardiology 73:43-49.
Elbaz-Alon Y, Morgan B, Clancy A, Amoako TN, Zalckvar E, Dick TP, Schwappach B, Schuldiner M (2014) The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. FEMS Yeast Research 14:1055-1067.
Morgan B (2014) Reassessing cellular glutathione homoeostasis: novel insights revealed by genetically encoded redox probes. Biochemical Society Transactions 42:979-984.
Ezerina D, Morgan B, Dick TP (2014) Imaging dynamic redox processes with genetically encoded probes. Journal of molecular and cellular cardiology Journal of Molecular and Cellular Cardiology 73:43-49.
2013
Morgan B, Ezerina D, Amoako TN, Riemer J, Seedorf M, Dick TP (2013) Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis. Nature Chemical Biology 9:119-125.
Bode M, Longen S, Morgan B, Peleh V, Dick TP, Bihlmaier K, Herrmann JM (2013) Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest. Antioxidants & Redox Signaling 18:1597-1612.
Fujikawa Y, Morgan B, Dick TP (2013) Fluorescent imaging of redox species in multicellular organisms. in Oxidative Stress and Redox Regulation , Jakob U, Reichmann D (eds), pp 1597-1612.
Bode M, Longen S, Morgan B, Peleh V, Dick TP, Bihlmaier K, Herrmann JM (2013) Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest. Antioxidants & Redox Signaling 18:1597-1612.
Fujikawa Y, Morgan B, Dick TP (2013) Fluorescent imaging of redox species in multicellular organisms. in Oxidative Stress and Redox Regulation , Jakob U, Reichmann D (eds), pp 1597-1612.
2012
Kojer K, Bien M, Gangel H, Morgan B, Dick TP, Riemer J (2012) Glutathione redox potential in the mitochondrial intermembrane space is linked to the cytosol and impacts the Mia40 redox state. The EMBO Journal 31:3169-3182.
2011
Morgan B, Sobotta MC, Dick TP (2011) Measuring E(GSH) and H2O2 with roGFP2-based redox probes. Free Radical Biology and Medicine 51:1943-1951.
2010
Braun NA, Morgan B, Dick TP, Schwappach B (2010) The yeast CLC protein counteracts vesicular acidification during iron starvation. Journal of Cell Science 123:2342-2350.
2009
Morgan B, Ang SK, Yan G, Lu H (2009) Zinc can play chaperone-like and inhibitor roles during import of mitochondrial small Tim proteins. The Journal of Biological Chemistry 284:6818-6825.
2008
Morgan B, Lu H (2008) Oxidative folding competes with mitochondrial import of the small Tim proteins. Biochemical Journal 411:115-122.
